(1)在优化的镁合金材料基础上开展支架用微管加工、支架结构设计与制造,及微管质量稳定化制备技术研究,建立血管支架用微管加工的质量标准和工艺控制标准。(2)研究加工成型工艺对镁合金支架用微管的力学性能以及尺寸精度的影响,调控其“三性”,制备出血管支架用精密微管,建立加工工艺标准;(3)基于有限元、降解过程和流固耦合分析,模拟并验证血管支架在植入和服役过程中的力学和降解行为,对支架结构进行优化设计;(4)优化支架激光加工和表面抛光工艺,实现镁合金支架的精密成型,制订相应的技术要求,建立镁合金血管支架的工艺流程和生产标准。
(1) On the basis of optimized magnesium alloy materials, research on the processing of microtubes for stents, the design and manufacture of stent structures, and the preparation technology of microtube quality stabilization are carried out on magnesium alloy microtubes. The purpose is to establish quality standards and process control standards for microtubule processing for vascular stents. (2) Research the influence of processing and forming process on the mechanical properties and dimensional accuracy of microtubes for magnesium alloy stents. It is possible to regulate its "three properties" and prepare precise microtubes for vascular stents, and finally establish the processing technology standard. (3) Based on finite element , degradation process and fluid-solid coupling analysis, we simulate and verify the mechanical and degradation behavior of vascular stents during implantation and service, and optimize the design of the stent structure; (4) Optimize the stent laser processing and surface polishing process to realize the magnesium alloy stent for precision molding, formulate corresponding technical requirements,and then establish the process flow and production standards of magnesium alloy vascular stents.