The effect of impurity elements in the rolling process of molybdenum slabs was studied, and the results showed that impurity elements mainly affected the dynamic recrystallization process of molybdenum during hot deformation. On the one hand, impurity atoms can pin dislocations to prevent the dynamic recovery of thermal deformation and delay continuous dynamic recrystallization (CDRX). On the other hand, most of the impurity atoms segregate at the grain boundary, which has a drag effect on the migration of the grain boundary, thereby inhibiting the growth of abnormal grains. However, the influence of impurities on the texture evolution of the molybdenum plate is not significant.