本发明属于生物材料及其在植入医疗器械中应用领域,具体涉及一种提高变形性生物镁合金植入器件耐蚀性的表面改性方法,在变形性生物可降解镁合金植入器件上制备耐蚀性涂层的表面改性,旨在提高变形性镁合金植入器件的耐蚀性能,进而有效延长其服役期。在纯镁或镁合金表面制备化学转化涂层,然后在化学转化涂层上制备可降解高分子涂层,并进行热处理封孔。本发明表面改性方法有效地降低了镁合金的降解速率,稳定了镁合金植入器件周围生物环境的pH值,降低了初期炎症及溶血现象发生的概率,提高了变形性可降解镁合金器件的植入成功率。本发明旨在解决可降解镁合金植入器件在应用过程中存在的较大变形处降解速度快、易腐蚀处 快速断裂的问题。
The present invention belongs to the biological materials and its applications in the implanted medical devices, including an improved deformation biological methods of surface modification of magnesium alloys implanted device corrosion resistance, the deformation of biodegradable magnesium alloy implanted device preparation of corrosion resistant coating on the surface modification, aimed at improving deformation magnesium alloy corrosion resistant performance of implanted devices, thus effectively prolong the conscription. The chemical transformation coating was prepared on the surface of pure magnesium or magnesium alloy, and then the degradable polymer coating was prepared on the chemical transformation coating, and the hole was sealed by heat treatment. The surface modification method of the invention can effectively reduce the degradation rate of magnesium alloy, stabilize the pH value of the biological environment around the implanted magnesium alloy device, reduce the probability of initial inflammation and hemolysis, and improve the implantation success rate of the deformable degradable magnesium alloy device. The invention aims at solving the problems of rapid degradation at large deformation and rapid fracture at easy corrosion in the application process of degradable magnesium alloy implanted devices.