本发明涉及医疗器械领域,尤其涉及一种能使降解支架在X光下显影的标记及其制备方法。采用生物相容性和显影效果均表现良好的钽作为制作显影标记的材料,通过表面处理,在不降低其X射线显影性和提高其生物相容性同时,完全避免了由于不同金属接触(显影点与可降解金属支架 )腐蚀带来的电偶腐蚀效应。本发明制备出多种尺寸规格的显影标记放置在不同规格的降解支架预留孔位置,在支架植入后,随着植入部位血管功能的逐步重建与自我修复,显影标记的侧面和上下表面分别被网丝和血管紧紧束缚住,在显影点和支架的表面可以有药物涂层包覆。该显影标记能够承受长时间的血管收缩运动和血流冲刷而不脱落,具有良好的医用安全性和简单的实际可操作性。
The invention relates to the field of medical devices, in particular to a mark enabling degradation scaffold to develop under X-ray and a preparation method thereof. Tantalum, which has good biocompatibility and development effect, is used as the developing marker material. Through surface treatment, the galvanic corrosion effect caused by the corrosion of different metal contact (developing point and degradable metal scaffold) is completely avoided without reducing its X-ray development and improving its biocompatibility. This invention was a variety of sizes imaging markers placed in the degradation of different specifications of stent hole position, after stenting with embedded parts blood vessel function reconstruction and repair itself gradually, enhancement of the tag side and up and down surface, respectively, to be shackled by mesh and vascular tightly, in developing point and surface can have drug-coated stent coated. The developing marker can withstand the vasoconstriction movement and blood flow erosion for a long time without falling off. It has good medical safety and simple practical operation.