本发明公开了吲哚嗪类抗蚀剂的制备方法，卤代化合物和吡啶衍生物、喹啉衍生物或异喹啉直接制取的N‑取代吡啶鎓盐，亚硝酸盐氧化剂存在下，制备出吲哚嗪鎓盐衍生物，缩短了现有技术制备吲哚嗪鎓盐衍生物的工艺流程；所有原料均可直接购买，且价格低廉；工艺流程中无须添加任何的过渡金属和碱，工艺流程也更加简单，成本明显降低；整个流程对于空气和湿气都不敏感，可在宽松的反应条件作常规操作；氧化剂本身及氧化还原产物均可溶于水，后处理简单环境危害低；可为生物、农药和材料领域制备相关产品，提供来源充裕价格较低的吲哚嗪鎓盐衍生物。

The invention discloses a preparation method of indolizine resist, N‑ substituted pyridinium salts directly prepared from halogenated compounds and pyridinium derivatives, quinoline derivatives or isoquinoline derivatives, and in the presence of nitrite oxidants, pyridinium indolizine derivatives are prepared. The technological process of preparing pyridinium indolazine derivatives by prior art was shortened. All raw materials can be purchased directly and at low prices; There is no need to add any transition metal and alkali in the process, and the process is simpler and the cost is significantly reduced. The whole process is not sensitive to air and moisture, and can be routinely operated under relaxed reaction conditions. The oxidant itself and the REDOX products are soluble in water, and the post-treatment is simple and the environmental harm is low. It can prepare related products for the biological, pesticide and materials sectors, providing adequate sources of inexpensive pyridine and indolizine salt derivatives.