除了有效的骨修复能力外，植入的支架对其他组织和器官也应无不良影响，特别是对心、肝、肾等主要器官。因此，采用苏木精和伊红染色法检测不同聚合物支架植入8周后的大鼠的心脏、肝脏和肾脏。从图6可以看出，P-PUU支架的植入没有明显的组织学异常或病变，提示P-PUU支架的体内生物安全性。

In addition to effective bone repair ability, the implanted scaffolds should have no malign effects on other tissues and organs, especially on those major organs such as heart, liver, and kidney. Therefore, the heart, liver, and kidney of the rats after implantation of various polymeric scaffolds for 8 weeks were examined by hematoxylin and eosin staining. Implantation of P-PUU scaffolds produced no obvious histological abnormality or lesion, suggesting desirable in vivo biosafety of P-PUU scaffolds.