一种医用钛表面梯度纳米银的制备方法，涉及医用钛表面涂层修饰。医用钛箔表面预处理；制备TiO₂纳米管；配制含银离子电解液；采用双极电化学反应实验，得医用钛表面梯度纳米银。在医用钛表面构筑梯度纳米银涂层结合传统电化学阳极氧化法和双极电化学法，通过选用合适的电解液配方和控制电化学参数获得颗粒梯度变化的纳米银，制得的TiO₂纳米管阵列形状规则，紧密排列。TiO₂纳米管阵列表面制得的纳米银颗粒尺寸梯度变化。在较短的时间内利用双极电化学法在钛纳米管表面一步制备得到梯度纳米银的颗粒，具有工艺简单、耗时短、易于实现和控制等特点。应用于纳米银颗粒抗菌的高通量筛选时，具有高效、快速的特点。

A method for preparing gradient nanosilver on a medical titanium surface includes the surface coating modification of medical titanium. Surface pretreatment of medical titanium foil; preparation of TiO₂ nanotubes; preparation of electrolyte containing silver ions; bipolar electrochemical reaction experiments are used to obtain gradient nanosilver on the surface of medical titanium. A gradient nanosilver coating on the surface of medical titanium was constructed, combining traditional electrochemical anodization and bipolar electrochemical methods, by selecting appropriate electrolyte formulations and controlling electrochemical parameters to obtain gradient-variable nanosilver particles and prepared TiO₂ nanotubes is regular and closely arranged. The size of the nanosilver particles prepared on the surface of the TiO₂ nanotube array changes in a gradient. In a relatively short period of time, the bipolar electrochemical method is used to prepare gradient nanosilver particles on the surface of the titanium nanotubes in one step, which has the characteristics of simple process, short time-consuming, easy implementation and control. When applied to high-throughput screening of antibacterial nano-silver particles, it has the characteristics of high efficiency and rapidity.