本发明公开了一种抗菌/抗骨肉瘤/促成骨多功能性钛基植入材料的制备方法；本发明首先通过微弧氧化处理在钛材表面构建锶离子掺杂的羟基磷灰石多孔涂层；然后将样本置于含2,5‑二羟基对苯二甲酸和硝酸镁的高压反应釜中，125℃条件下反应24h，在表面获得金属有机骨架涂层；所获得Mg‑MOF74/Sr‑HA复合涂层修饰样本呈现出优越的抗菌、抗骨肉瘤及促成骨特性，具有良好的临床应用前景。

The invention discloses an anti-bacteria/anti-osteosarcoma/osteogenesis promotion multifunctional titanium-based implant material and a preparation method thereof. The preparation method includes thefollowing steps: constructing a strontium ion-doped hydroxyapatite porous coating on the surface of a titanium material by micro-arc oxidation treatment; then placing a sample in a high-pressure reaction kettle containing 2,5-dihydroxyterephthalic acid and magnesium nitrate, performing a reaction for 24 h at 125 DEG C, and obtaining a metal organic skeleton coating on the surface. The obtained modified sample of Mg-MOF74/Sr-HA composite coating exhibits superior properties of anti-bacteria, anti-osteosarcoma and osteogenesis promotion, and had good clinical application prospects.