本发明属于基因和RNA的功能与应用领域，涉及MACC1‑AS1探针在制备用于预测胃癌临床预后的诊断试剂中的应用。本发明还提供一种用于预测胃癌临床预后的诊断试剂盒，该试剂盒包括MACC1‑AS1探针。本发明首次揭示了在胃癌中，MACC1‑AS1与胃癌患者预后相关，与患者临床分期、TNM分期正相关；是胃癌细胞无糖应激时，产生抗氧化物质维持氧化还原平衡、促进糖酵解进行维持糖代谢、维持生存减少凋亡的重要分子。因此，本发明为研究胃癌患者临床预后相关因素、为非编码RNA的临床应用提供了理论依据和临床基础。  

The invention belongs to the function and application field of gene and RNA, and relates to the application of MACC1 AS1 probe in preparing diagnostic reagent for predicting clinical prognosis of gastric cancer. The invention also provides a diagnostic kit for predicting the clinical prognosis of gastric cancer, which includes MACC1 AS1 probe. The invention reveals for the first time that in gastric cancer, MACC1 AS1 is correlated with the prognosis of gastric cancer patients, and is positively correlated with the clinical stage and TNM stage of patients; It is an important molecule that produces antioxidant substances to maintain REDOX balance, promote glycolysis to maintain glucose metabolism, maintain survival and reduce apoptosis in gastric cancer cells without sugar stress. Therefore, the invention provides a theoretical basis and clinical basis for the study of clinical prognostic factors of gastric cancer patients and the clinical application of non-coding RNA.