本发明公开了一种多巴胺改性纳米粉体并嵌入有机物的多孔抗肿瘤骨修复双功能复合支架及其制备方法。该方法包括如下步骤：在氨水环境下用盐酸多巴胺修饰纳米羟基磷灰石表面，得到微纳结构羟基磷灰石/聚多巴胺复合物，加入羧甲基壳聚糖共混，得到复合浆料，通过3D打印等方式得到复合支架，用质量分数为10%的CaCl2溶液快速交联，再用质量分数0.5%的京尼平溶液交联，随后经过多次离心洗涤、干燥，得到所述复合支架。该方法通过多巴胺修饰微纳结构羟基磷灰石，不仅赋予了材料光热抗肿瘤的性能，还提高了纳米粉体在羧甲基壳聚糖中的分散性，同时也增强了支架的力学性能。本发明对骨肿瘤导致的骨缺损修复具有重要的临床意义。

The invention discloses a dopamine modified nano-powder porous anti-tumor bone repair dual-function composite scaffold with an embedded organic matter and a preparation method thereof. The method comprises the following steps that under the environment of ammonium hydroxide, dopamine hydrochloride is adopted for modifying the surface of nanometer hydroxyapatite, a micro-nano structure hydroxyapatite/poly-dopamine compound is obtained, carboxymethyl chitosan is added for mixing, composite paste is obtained, the composite scaffold is obtained in 3D printing and other modes, a CaCl2 solution withthe mass fraction being 10% is adopted for rapid cross-linking, a genipin solution with the mass fraction being 0.5% is adopted for cross-linking, then, repeated centrifuging, washing and drying areperformed, and the composite scaffold is obtained. According to the method, due to the dopamine modified micro-nano structure hydroxyapatite, the photo-thermal anti-tumor performance is given to the material, the dispersity of nano-powder in carboxymethyl chitosan is improved, and meanwhile the mechanical property of the scaffold is enhanced. The scaffold is of great clinic significance in repairof bone defects caused by bone tumors.