本发明提供了一种聚氨酯海绵材料及其制备方法、应用和聚氨酯海绵制品,涉及生物材料技术领域,本发明提供的聚氨酯海绵材料,包括锶硼生物活性玻璃和聚氨酯。其具有良好的生物活性、生物降解性和生物相容性,可作为创面修复和治疗一体化的复合人工皮肤。并且能够有效地诱导创面血管化和皮肤再生、原位地迅速修复皮肤损伤,且不易造成粘连,避免二次创伤,从而在促进创面修复方面达到了更为良好的效果。本发明提供的聚氨酯海绵材料的制备方法,简单易操作、塑形方便、聚合温度低、便于应用,且制备得到的聚氨酯海绵材料具有良好的生物活性、生物降解性和生物相容性。
The invention provides a polyurethane sponge material, a preparation method and an application of the polyurethane sponge material and a polyurethane sponge product and relates to the technical fieldof biological materials. The polyurethane sponge material comprises strontium-boron bioactive glass and polyurethane, has good bioactivity, biodegradability and biocompatibility and can be used as composite artificial skin for wound repair and treatment integration. Besides, the polyurethane sponge material can effectively induce wound vascularization and skin regeneration and quickly repair skininjury in situ, cannot cause adhesion and avoid secondary wounds and has better effects for promoting wound repair. The preparation method of the polyurethane sponge material is simple, easy to operate, convenient to shape, low in polymerization temperature and convenient to apply, and the prepared polyurethane sponge material has good bioactivity, biodegradability and biocompatibility.