本发明公开了一种仿生的羟基磷灰石粉体/明胶/海藻酸钠复合3D打印支架及其制备方法。该仿生3D支架的制备方法包括:(1)具有仿生分级结构羟基磷灰石粉体的制备;(2)羟基磷灰石粉体/明胶/海藻酸钠复合浆料的制备;(3)仿生3D打印支架的制备。本发明利用3D打印技术,制备得到的机/无机复合三维打印支架的外部尺寸可控,生物相容性良好,并充分模拟了天然骨组织的成分和多级结构,赋予材料可控的力学强度;复合支架的微纳多级结构具有较高的成骨活性和骨诱导性,多级孔结构可以有效诱导组织和血管的长入,促进骨组织的再生修复
The invention discloses a biomimetic hydroxylapatite powder/gelatin/sodium alginate composite 3D print bracket and a preparation method thereof. The preparation method of the biomimetic 3D bracket comprises the steps of (1) preparing hydroxylapatite powder having a biomimetic classified structure; (2) preparing hydroxylapatite powder/gelatin/sodium alginate composite pulp; and (3) preparing the biomimetic 3D print bracket. According to the biomimetic hydroxylapatite powder/gelatin/sodium alginate composite 3D print bracket and the preparation method thereof disclosed by the invention, a 3D printing technique is utilized, the prepared organic/inorganic composite three-dimensional print bracket is controllable in outside size and good in biocompatibility, components and a multi-level structure of natural bone tissue are sufficiently simulated, and controlled mechanical strength is given to materials; and the micro-nano multi-level structure of the composite bracket has higher osteogenesis activity and osteoinductive, a multi-level pore structure can effectively induce ingrowth of tissue and blood vessels, and regeneration and repair of the bone tissue are promoted.