Influences of albumin on in vitro corrosion behaviour of pure Zn in artificial plasma up to 28 days were investigated. Pure Zn undergoes uniform corrosion and a complex of albumin and zinc oxide/hydroxide forms on the surface. At the initial immersion stage, rapid adsorption of albumin retards the corrosion of pure Zn.

However, the corrosion is promoted due to dissolution of metal matrix after 3 days. And 7 days later, Zn corrosion is obstructed by the complex accumulation on the surfaces. Profound understanding of pure Zn corrosion will encourage further exploration of Zn alloys in potential clinical application.