本发明公开了一种具有非均质多孔仿生天然骨结构的生物活性陶瓷支架及其制备方法。该方法借助先进的直接挤出成型工艺对生物活性陶瓷浆料直接打印成型，构建出外部致密到内部疏松连续性变化的多孔结构，实现了对天然骨结构的仿生。其制备方法如下：（1）3D打印用生物活性陶瓷粉体的制备；（2）生物活性陶瓷浆料的制备；（3）非均质多孔仿生天然骨结构生物陶瓷支架的打印；（4）支架的干燥和烧结，得具有非均质多孔仿生天然骨结构的生物活性陶瓷支架。本发明采用自制3D打印专用陶瓷粉体，结合3D打印技术的优势，实现了对陶瓷支架渐变孔径尺寸的精确控制，解决了非均质结构精确构建的难题，对于骨缺损再生修复意义重大。

The invention discloses a biological activity ceramic bracket with a heterogeneous porous bionic natural bone structure and a preparation method of the biological activity ceramic bracket. According to the preparation method of the biological activity ceramic bracket, biological activity ceramic slurry is directly printed and molded by virtue of an advanced direct extrusion molding technology, a porous structure of continuous changing from external compactness to internal loose is established, and bionics of the natural bone structure is realized. The preparation method of the biological activity ceramic bracket comprises the following steps of (1) preparation of biological activity ceramic powder for 3D printing, (2) preparation of the biological activity ceramic slurry, (3) printing of the biological activity ceramic bracket with the heterogeneous porous bionic natural bone structure, and (4) drying and sintering of the bracket, and the biological activity ceramic bracket with the heterogeneous porous bionic natural bone structure is obtained. According to the biological activity ceramic bracket with the heterogeneous porous bionic natural bone structure and the preparation method of the biological activity ceramic bracket, the self-regulating biological activity ceramic powder special for 3D printing is adopted, the advantage of 3D printing technology is combined, accurate control of gradient pore size of the ceramic bracket is realized, the problem of heterogeneous structure accurate establishment is solved, and great significance is achieved for regeneration and repairof bone defects.