本发明实施例提供一种复合生物玻璃的粘附温敏水凝胶，包括以下重量百分比的组分：PDLLA‑PEG‑PDLLA三嵌段聚合物25‑40％、多巴胺改性的季铵化壳聚糖1‑1.25％、生物玻璃1‑5％，以及余量去离子水。该复合生物玻璃的粘附温敏水凝胶具有良好的黏附性、抗菌性和生物相容性。所述复合生物玻璃的粘附温敏水凝胶可以自粘附于皮肤创伤表面，有利于促进皮肤再生，伤口修复。本发明还提供了所述复合生物玻璃的粘附温敏水凝胶的制备方法和应用。该制备方法工艺简单，产率高，可适用于大规模的工业化生产，由所述制备方法制备得到的复合生物玻璃的粘附温敏水凝胶具有良好的黏附性、抗菌性和生物相容性，在制备用于皮肤创伤愈合的药物中具有广阔的应用前景。

The embodiment of the invention provides an adhesion thermo-sensitive hydrogel of composite bioglass. The adhesion thermo-sensitive hydrogel is prepared from the following components in percentage byweight: 25-40% of PDLLA-PEG-PDLLA triblock polymer, 1-1.25% of dopamine modified quaternized chitosan, 1-5% of bio-glass and the balance of deionized water. The adhesion thermo-sensitive hydrogel of the composite bioglass has good adhesion, antibacterial property and biocompatibility. The adhesion thermo-sensitive hydrogel of the composite bioglass can self-adhere to the surface of the skin wound,and is beneficial for promoting skin regeneration and wound repair. The invention further provides a preparation method and application of the adhesion thermo-sensitive hydrogel of the composite bioglass. The preparation method is simple in process and high in yield, and is suitable for large-scale industrial production. The adhesion thermo-sensitive hydrogel of the composite bioglass prepared bythe preparation method has good adhesion, antibacterial property and biocompatibility, and has broad application prospects in the preparation of drugs for skin wound healing.