使用等离子喷涂火焰后处理技术，对所制备的50% Nb2O5-TiO2涂层进行不同工艺参数的等离子火焰后处理，从而形成了不同的材料表层拓扑结构。通过X射线衍射技术对一系列不同工艺参数处理后取下的涂层，进行分析，并整理出物相变化的系统性规律；利用SEM对涂层进行观察，并将图像进行抽象化处理、计算分析 。

不同类型的巨噬细胞对心脏成纤维细胞的迁移和活化性能具有不用的影响。其中M0、M2a和M2c型巨噬细胞可以显著促进成纤维细胞迁移，而M1巨噬细胞和M2b巨噬细胞可以显著抑制成纤维细胞的迁移，减轻再灌注损伤后的心脏纤维化。而M2b型巨噬细胞也能显著抑制成纤维细胞活化，进一步减轻再灌注损伤后的心脏纤维化，从而促进了损伤后的心脏修复。

The 50%Nb2O5-tio2 coating was posttreated by plasma spraying flame with different process parameters, thus forming different topological structures of the material surface. X-ray diffraction technology was used to analyze the coating after a series of different processing parameters, and the systematic rule of phase change was sorted out. The coating was observed by SEM, and the image was abstracted and calculated.

Different types of macrophages have different effects on migration and activation of cardiac fibroblasts. Among them, M0, M2a and M2c macrophages can significantly promote the migration of fibroblasts, while M1 macrophages and M2b macrophages can significantly inhibit the migration of fibroblasts and reduce cardiac fibrosis after reperfusion injury. M2b macrophages can also significantly inhibit the activation of fibroblasts and further reduce cardiac fibrosis after reperfusion injury, thus promoting cardiac repair after injury.